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脓毒症控制血糖治疗的研究进展

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摘要 由于感染,应激等因素的存在脓毒症患者常伴有血糖的升高。应激性高血糖曾被认为是机体的自我保护机制。直到2001年Van den Berghe等人的研究表明,强化胰岛素治疗控制血糖会带来临床益处,由此引发了一系列的临床和动物研究验证其研究结果并探讨其内在机制。但结果却不尽相同。大家注意到在有限证据下对脓毒症患者进行强化胰岛素治疗还有许多问题需要探讨。
出处 《泰山医学院学报》 CAS 2011年第10期793-796,共4页 Journal of Taishan Medical College
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  • 1姚咏明,孟海东.脓毒症高血糖与胰岛素强化治疗策略[J].中国危重病急救医学,2006,18(2):68-70. 被引量:84
  • 2Wallington J, Ning J, Titheradge MA. The control of hepatic gly- cogen metabolism in an in vitro model of sepsis[J]. Mol Cell Bio- them 2008,308 : 183-92.
  • 3Atsumi T, Cho YR, Leng L, McDonald C, Yu T, Danton C, et al. The proinflammatory cytokine macrophage migration inhibitory factor regulates glucose metabolism during systemic inflammation [ J]. J Immuno1,2007,179 : 5399-406.
  • 4Marik PE, Raghavan M. Stress2hyperglycemia, insulin and im- mu2 nomodulation in sepsis [ J ]. Intensive Care Med, 2004, 30( 5 ) :748-756.
  • 5Bader MS, Hinthorn D, Lai SM, Ellerbeck EF. Hyperglycaemia and mortality of diabetic patients with candidaemia [ J ]. Diabet Med ,2005,22 : 1252-7.
  • 6Ginde AA, Rhee SH, Katz ED. Predict ns of outcome in geriatric patients with urinary tract infections[ J]. J Emerg Med,2004,27: 101-8.
  • 7Bader MS. Hyperglycemia and mortality in elderly patients with Staphylococcus aureus bacteremia [ J ]. South Med J, 2007,100 : 252-6.
  • 8Leonidou L, Mouzaki A, Michalaki M, DeLastie AL, Kyriazopou- lou V, Bassaris HP, et al. Cytokinc production and hospital mor- tality in patients with sepsis-induced stress hyperglycemia [ J ]. J Infect ,2007,55 : 340-6.
  • 9van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyn- inckx F, Schetz M, et al. Intensive insulin therapy in the critically ill patients[J]. N Engl J Med,2001,345 :1359-67.
  • 10Brunkhorst FM, Engel C, Bloos F,et al. Intensive insulin thera- py and pentastarch resuscitation in severe sepsis [ J ]. N Engl J Med,2008,358 : 125-39.

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