皮肤溃疡创面的中西医基础与临床研究近况

Chinese & Western Medicine Basis of Skin Ulcerous Wound and Status Quo of Clinical Studies

皮肤溃疡是临床最常见的慢性损伤之一,其发病机制复杂,至今尚未完全阐明,不同原因所致的皮肤溃疡创面病因学不同,发病机制也各有差异。在临床上,治疗皮肤溃疡的方法很多,局部治疗是主要手段之一,但临床疗效并不尽人意,是临床创面修复的一大难题。促进溃疡创面的修复愈合是治疗慢性皮肤溃疡的基本任务,而寻找安全有效的治疗方法是目前研究的热点问题。近年来,在中西医基础与临床科研人员的努力下,有关慢性皮肤溃疡的基础研究和临床治疗的许多方面已取得长足进步,有力地推动了皮肤创面愈合整体水平的提高。本文旨在对近年来慢性皮肤溃疡创面的中西医基础与临床研究近况作一概述。

Skin ulcer is one of the most common chronic injuries in clinic, with the very complex pathogenesis which has not been fully understood since skin ulcers caused by different reasons have different wound etiology and patho-genesis. In clinic, there are many approaches to treat skin ulcers, and topical treatment is one of the major method, but its clinical therapeutic effect is unsatisfactory. There is unmet need for clinical skin ulcer wound repair. To promote the wound healing is the basic task of treating chronic skin ulcers and thus, to find out a safe and effective treatment becomes the locus of present studies. In recent years, through the collaborated efforts of basic and clinical researchers at Chinese and western medical fields, the basic research anti clinical studies related to chronic ulcers have made great progress, which strongly promoted the overall level of skin wound healing. This paper aims tu review Chinese ＆ western medicine basis of skin ulcerous wound and status quo of clinical studies in recent years.