应用口腔修复膜修复口腔黏膜组织术后缺损

Clinical Effects of Xenogenic Acellular Dermal Matrix on Repairing Postoperative Residual Defects of Oral Mucosal Tissue

目的评价口腔修复膜(异种脱细胞真皮基质修复膜)在口腔黏膜组织术后缺损修复中的应用及其临床效果。方法收集2009年1月-2010年5月应用异种脱细胞真皮基质修复膜进行口腔黏膜组织术后缺损修复的33例患者的临床资料,对其术后的临床疗效进行追踪随访并进行其功能评价。结果 33例患者术后随访10～24个月,平均随访16个月;33例患者黏膜组织缺损修复均获得成功,术后12～14 d未见修复膜脱落,愈合良好。结论应用异种脱细胞真皮基质修复膜能够起到早期覆盖创面,促进创面愈合,减轻瘢痕形成的作用。其操作简单易行,是一种值得推广的修复方法。

Objective To evaluate the clinical application and effect of xenogenic acellular dermal matrix in repairing the postoperative residual defects of oral mucosal tissue.Methods Thirty three cases with oral mucosal tissue defects were treated with xenogenic acellular dermal matrix.All patients were followed up for 10 to 24 months（mean 16 months）,and the functions were assessed.Results The operations succeeded in all patients.All transplants survived well 12 to 14 days after the operation,and the wounds were healed well.Conclusion Xenogenic acellular dermal matrix is a valuable biomaterial for repairing oral mucosal defects through covering and protecting wound surface early,which shortens the healing time of wound surface and decreases occurrence of production of scar.