摘要
目的比较剖宫产术后蛛网膜下腔注射极少量吗啡与应用舒芬太尼PCIA对产妇的镇痛效果、胃肠功能、免疫、泌乳及母乳喂养新生儿生理状况影响。方法选择2005年11月-2006年1月择期行剖宫产手术的孕妇30例,随机分为吗啡组和舒芬太尼组,每组15例。观察两组给药方法产妇的麻醉时间、术中输液量、失血量;新生儿神经行为能力评分;产妇免疫功能及不良反应、排气时间和开始分泌初乳时间的差异。结果两组产妇在麻醉时间、术中输液量和出血量差异无显著性;24h内VAS评分差异无显著性;两组新生儿在术后不同时段的NBNA评分均>35分,组间比较差异无著性;两组产妇IL-2和IL-6术前术后组间比较均无著性差异,但组内比较IL-6术后均较术前明显增高,有显著性差异(P<0.05)。结论剖宫产术后镇痛中鞘内注射吗啡0.2mg与舒芬太尼静脉PCIA1.5μg·mL-1均能获得满意的镇痛效果。
Objective To investigate the effects of morphine subarachnoid anesthesia and sufentanyl patients-control intravenous analgesia（PCIA） in postcesarean analgesia on women and infants.Methods from Nov 2005 through Jan 2006,30 ASA Ⅰ-Ⅱ normal pregnant women undergoing selective caesarean section were randomly assigned to either group A（morphine subarachnoid anesthesia,n=15） and group B（sufentanyl PCIA,n=15）.Pain score（VAS 0-10）,newborn behavior-neural assessment（NBNA）,adverse effects of the morphine or sufentanyl,and the immune changes were assessed for these women.Results there were no differences among Anesthesia time,fluid volume for transfusion and blood loss during operation,NBNA,immune changes,and so on between group A and group B.intragroup IL-6 is higher in Before cesarean section than in postcesarean section（P0.05）.Conclusion A satisfied analgesic effect of postcesarean section can obtained in both two group.
出处
《临床药物治疗杂志》
2011年第6期21-24,共4页
Clinical Medication Journal
关键词
鞘内注射
吗啡
剖宫产
舒芬太尼
PCIA
Intrathecal injection
Morphine
Cesarean section
Sufentanil
PCIA
