氰醇碳酸脂的制备及作为酰基负离子等效剂的应用

The Preparation of Cyano-Carbonates and Its Application as Acyl-Anion Equivalents

亲核酰化反应是近年来人们在研究有机化合物极性翻转(Umpolung)时所注意到的一类新型反应,它能使许多用经典的方法难以实现的有机合成反应得以顺利进行,还可简化合成的途经,因此。

Cyano-Carbonates, conveniently prepared in excellent yield by in situ trappingof cyanohydrin anions with chloroformates under PTC conditions, have been found to beefficient acyl-anion equivalents. The alkylation of α-cyanocarbonate afforded a convenientmethod for aldehyde-ketone conversions.