80例胆汁反流性胃炎的临床研究

Clinical investigation of 80 cases of bile reflux gastritis

目的:探讨胆汁反流性胃炎的发病原因及其药物治疗的疗效。方法:回顾性本院在2009年9月～2011年4月收治的80例胆汁反流性胃炎患者,患者分为铝碳酸镁组及奥美拉唑组+铝碳酸镁组进行治疗。结果:铝碳酸镁组的临床表现有效率为87.5%,胃镜疗效有效率为85.0%;奥美拉唑+铝碳酸镁组的临床表现有效率为95.0%,胃镜疗效有效率为95.0%。奥美拉唑+铝碳酸镁组显著优于铝碳酸镁组,差异有统计学意义;两组均无不良反应发生。结论:胆囊疾病和胃部手术为胆汁反流性胃炎的两大病因,奥美拉唑+铝碳酸镁可有效缓解胆汁反流性胃炎的临床症状,值得临床推广。

Objective：To investigate the pathogen and efficacy of bile reflux gastritis.Methods：80 cases of bile reflux gastritis patients from September 2009 to April 2011 in our hospital were retrospectively analyzed who were divided into hydrotalcite and omeprazole group and omeprazole group.Results：The efficacy in symptoms and gastroscope of omeprazole group were 87.5% and 85.0% which were obviously lower than that of hydrotalcite and omeprazole group which were both 95.0%（P0.05）.The effects of hydrotalcite and omeprazole group were significantly better than the omeprazole group,difference was statistically significant;There were no adverse reactions in two groups.Conclusion：Gallbladder disease and gastreetomy are the main pathogens.And the hydrotalcite and omeprazole can effectively relieve the clinical symptoms of bile reflux gastritis which deserves clinical promotion.