异丙酚不同诱导速度在无痛人工流产术中麻醉效果的观察

Observation of effect of propofol induced velocity in different anesthesia induced abortion

目的:观察异丙酚不同诱导速度对无痛人工流产术的麻醉效果及不良反应。方法:将90例孕妇随机分为A、B、C3组各30例,静脉注射2μg/kg芬太尼后以不同诱导速度注入异丙酚,A组诱导速度为6mg/(kg·min),B组诱导速度为3mg/(kg·min),C组诱导速度为2mg/(kg·min),观察麻醉效果、心电监护数据、异丙酚总用量、呼吸抑制情况、苏醒时间等。结果:麻醉效果,C组24例优,A、B组分别29例优,C组麻醉效果与A、B组比较,差异有统计学意义(P<0.05);呼吸抑制情况:C组仅1例发生呼吸抑制,A组和B组分别有10例和4例发生呼吸抑制,C组与A、B组比较,差异有统计学意义(P<0.05)。结论:异丙酚以较快速度诱导患者苏醒快,异丙酚用量少,但呼吸抑制也相应增加,建议临床以3mg/(kg·min)的速度诱导麻醉效果好且安全。

Objective：To observe the effect of propofol induced velocity in different anesthesia induced abortion.Methods：90 cases of pregnant women were randomly divided into A,B,C three groups of 30 patients,propofol induced velocity in different anesthesia induced abortion observed effect,A group of induced velocity of 6 mg/（kg·min）,B group of induced velocity of 3 mg/（kg·min）,C group of induced velocity of 2 mg/（kg·min）,observed the effect of anesthesia,ECG data,the total amount of propofol,respiratory inhibition,recovery time,etc.Results：Anesthesia,C group was 24 cases of superior,A,B groups were 29 cases of superior,the difference of anesthetic effect in group C and A,B group was significant（P0.05）;Inhibition of respiration：C group,only a case of respiratory depression,group A and group B were 10 cases and 4 cases of respiratory depression,difference of group C and A,B group was significant（P0.05）.Conclusion：Propofol induced a faster rate in patients wake up faster,propofol with less,however,a corresponding increase in cases of respiratory depression,the speed of the proposed clinical to 3 mg/（kg·min） effective and safe induction of anesthesia.