尿激酶静脉溶栓治疗急性心肌梗死42例疗效观察

Clinical observation of urokinase thrombolysis on 42 cases with acute myocardial infarction

目的:探讨尿激酶静脉溶栓治疗急性心肌梗死的疗效。方法:选择本院急性心肌梗死患者84例,将上述患者随机分为两组,观察组和对照组各42例。对照组采用常规治疗,观察组患者在对照组治疗基础上,实施尿激酶静脉溶栓治疗。结果:观察组冠脉再通率与对照组比较,差异有统计学意义(P<0.05);观察组心力衰竭发生率、梗死后心绞痛发生率和死亡率分别与对照组比较,差异有统计学意义(P<0.05)。结论:急性心肌梗死采用尿激酶静脉溶栓,冠脉再通率高,患者心脏不良事件显著减少,临床效果显著。

Objective：To explore the clinical efficacy of urokinase thrombolysis on acute myocardial infarction.Methods：84 cases with acute myocardial infarction were selected,and were divided into observation group and control group 42 cases in each.Routine therapy was given to control group,and urokinase thrombolysis was used to observation group.Results：There was statistical difference of reperfusion rate of coronary after treatment in observation group compared with that in control group（P〈0.05）;The incidence of heart failure,angina pectoris after myocardial ifarction and mortality compared with those in control group,there were statistical differences（P〈0.05）.Conclusion：Urokinase thrombolysis on acute myocardial infarction has high reperfusion rate of coronary,and decrease the adverse cardiac events,the clinical efficacy is significant.