急性心肌梗死溶栓过程中镇静治疗的临床应用

Clinical application of sedation treatment in thrombolytic process of acute myocardial infarction

目的:研究探讨镇静治疗在急性心肌梗死溶栓过程中的应用疗效和安全性。方法:临床选择2008年2月～2009年10月入住本院心血管科确诊为急性心肌梗死患者共计176例,随机分为试验组和对照组各88例。试验组患者行一般常规溶栓处理过程兼用地西泮静脉注射镇静治疗,对照组行常规治疗或镇静剂镇痛,两组患者治疗3～5d后停止用药,1周内观察病情变化。结果:试验组各项指标总有效率达到86.5%,而对照组总有效率仅为59.16%,治疗组与对照组比较,差异具有统计学意义(P<0.05)。结论:镇静治疗方法在急性心肌梗死溶栓过程中安全、方便、行之有效,值得临床推广使用。

Objective：To study the curative effects and safety of sedation treatment in the thrombolytic process of acute myocardial infarction.Methods：176 patients hospitalized in the cardiovascular department of our hospital from February 2008 to October 2009 and diagnosed with acute myocardial infarction were randomly divided into the experimental group and the control group,with 88 patients for each group.The experimental group received general conventional treatment plus sedation treatment of diazepam through intravenous injection while the control group received conventional treatment or sedation for analgesia.Both groups stopped medication after treatment for 3 to 5 days and the patient＇s conditions within one week were observed.Results：The total effective rate of various indicators of the experimental group was 86.5% while that of the control group was only 59.16%,with statistical significance between the two groups（P〈0.05）.Conclusion：Sedation treatment is safe,convenient and effective in the thrombolytic process of acute myocardial infarction,thereby worthy of clincial application and promotion.