原发性肝癌TACE后动脉化疗联合热疗的疗效观察

A clinical observation of intra-arterial chemotherapy combined with thermotherapy for primary liver cancer after TACE

目的观察原发性肝癌经动脉行化学栓塞术(TACE)与肝动脉留管化疗同步局部高频热疗治疗的临床疗效及其毒副反应。方法 60例患者分为A、B两组,A组30例单纯行TACE治疗、B组30例行TACE后动脉留管化疗联合局部高频热疗,观察比较两组患者的临床效果。结果治疗后B组在肿瘤病灶变化、卡氏评分、疼痛缓解等方面均优于A组,且B组未增加毒副反应。结论行TACE后动脉留管化疗联合局部高频热疗可增加治疗有效率、缓解疼痛、提高患者的生活质量,是治疗原发性肝癌的一种安全、有效的治疗方法。

Objective To observe curative effect and subsidiary reaction of 60 primary liver cancer patients who were treated by TACE and artery chemotherapy after TACE,which combine concurrently partial high-frequency thermotherapy. Methods 60 cases were divided into A and B groups. 30 cases in A group were treated only by TACE. 30 cases in B group were treated by artery chemotherapy after TACE and combined concurrently partial high-frequency thermotherapy. The clinic effective of two groups were compared. Results The changing about volume of tumor,Carinii Scores, easement of pain in group B were all better than that in group A. And there was no increasing of subsidiary reaction in group B. Conclusions Treatment about chemotherapy through hepatic artery after TACE,combine local high-frequency thermotherapy could increase efficient,and relieve pain, and improve life quality of patient, accordingly lengthen life span of patient, which was a kind of safe and effective therapy.