影响侧脑室脑膜瘤手术疗效的多因素分析

Analysis of Multiple Factors Affecting Lateral Ventricular Meningioma Surgery

目的:探讨影响侧脑室脑膜瘤手术疗效的因素,从而更好的促进侧脑室脑膜瘤的手术治疗。方法:回顾性分析侧脑室脑膜瘤显微手术30例的临床病理特征与预后情况,其中KPS>70分表示为预后良好,KPS≤70分表示为预后不良。对各性别、年龄、部位、肿瘤大小、病理分型及术后有无并发症因素与预后进行x2检验与用Logistic回归分析其影响因素。结果:单因素分析表明肿瘤部位、病理分型及术后有无并发症对侧脑室脑膜瘤的预后有明显影响,P<0.05,差异有统计学意义。经Logistic回归分析,最终进入模型的影响因素有2个,它们分别是肿瘤部位和术后有无并发症,其P值均小于0.05。结论:在显微手术下,侧脑室脑膜瘤大部分可以全切并取得了较好的远期疗效。肿瘤部位和术后有无并发症是影响预后的一个重要因素,及时处理并发症能显著地改善预后。

Objective： To explore the multiple factors which affect the lateral ventricular meningioma surgery, so as to further promote the operational treatment of lateral ventricular meningioma. Mothods： Retrospectively analyzed the clinical pathological charact- eristics and prognosis of 30 patients who underwent microsurgery for lateral ventricle meningioma. KPS 〉70 indicated good prognosis and KPS≤ 70 not good. χ^2 test was applied to various clinical pathological characteristics （Gender, age, location, tumor size, pathological type and postoperative complications）and prognosis. And logistic regression analysis method was used to analyze the influencing factors. Results： By single factor analysis, prognosis was related to tumour position, group of pathology typing and postsurgical complication （P〈0.05）; differences had statistical significance. Logistic regression analysis showed two factors finally enter the model and they were tumour position and postsurgical complication （P〈0.05）. Conclusion： Under microsurgery, the most of lateral ventricular meningioma can be removed with a fine long-term effect. Tumour position and postsurgical complication are two crucial factors affecting prognosis; promptly treating complication could significantly improve prognosis.