美沙酮维持治疗人员HIV、HCV和TP情况分析——云南省晋宁县美沙酮服药人员调查

Analysis to HIV, HCV, TP infection status of MMT outpatient medication person in Jinning county of Yunnan province

[目的]了解晋宁县美沙酮维持治疗门诊服药人员艾滋病病毒(HIV)、丙型肝炎病毒(HCV)和梅毒(TP)感染情况,为制定吸毒人员艾滋病综合防治措施提供依据。[方法]选取晋宁县美沙酮门诊2005年6月至2011年5月31日所有服药人员为调查对象,征得被调查人员知情同意后,进行HIV、HCV、TP血清学检测,采用EXcel 2003建立数据库,随机抽取10%进行核查,使用SPSS17.0进行数据分析。[结果]共调查321名美沙酮服药人员,其中男性290人,女性31人,HCV阳性率为85.05%,HIV阳性率为52.65%,TP阳性率为2.18%,不同年龄段HIV和HCV感染情况差异有统计学意义(P<0.01),30岁～39岁年龄阶段HIV、HCV及TP阳性检出率最高分别为59.28%、86.60%和2.06%;不同吸毒方式HCV感染情况差异有统计学意义(P<0.001),静脉注射合并口吸者HIV、HCV、TP阳性检出率均分别为54.10%、87.87%和2.30%;不同服药年限HCV感染情况差异有统计学意义(P<0.05)。[结论]年龄、吸毒方式是影响调查对象HIV阳性检出率的因素,年龄、服药方式及服药年限是影响调查对象HCV阳性检出率的因素;服药年限是影响TP阳性检出率的因素。应继续推进美沙酮维持治疗、安全套发放和清洁针具交换,采取综合防治措施,从传播途径上切断疾病的传播与扩散。

Objective To know HIV, HCV, TP infection status and related effecting factors of MMT outpatients medication person so as to provide the evidence for formulating AIDS integrated control measures to drug addicts. Methods Having selected all medication person as investigation subject in Jun. 2005 - May. 31, 2011 in MMT outpatient in Jinning county. The contents include serology blood test of H1V, HCV. Adopted Excel 2003 to set up data base. Random selected 10% to inspect and analyzed data by SPSS17.0. Results The total MMT medication person were 321,290 were male and 31 were female, HCV positive rate was 85.05%, HIV positive rate was 52.65%, TP positive rate was 2.18%. There is statistic significance in different age group of HIV and HVV infection difference status（P 〈 0.01）. HIV, HCV, TP highest positive rate was 59.28%, 86.60% and 2.06% between the age from 30 to 39; There is statistic significance in different drug taking way of HCV infection difference status（P 〈 0.001）. HI-V, HCV, TP of both mainline and mouth sucker which positive rate was 54.10%, 87,87% and 2.30%; There is statistic significance in different medicine taking time of HCV infection difference status （p〈0.05）. Conclusions Age and drug taking way are the factors of effecting HIV positive relevance ratio to the respondents. Age, medicine taking way and time are the factors of HCV positive relevance ratio. Medicine taking time is the factors of TP positive relevance ratio. It is need to promote MMT, provide condom and exchange clean needle syringe, Take integrated control measures to cut off disease ~an_smission and spread from transmission path.