核素骨显像对肺癌骨转移诊断的价值

Value of radionuclide bone imaging for bony metastasis in lung cancer

目的：了解核素骨显像对诊断肺癌骨转移的价值。方法：我院１９９４～１９９８ 年所做肺癌骨显像２８０ 例中原发灶经病理证实的１０８ 例（鳞癌５９ 例，腺癌２９ 例，未分化癌２０ 例）全身骨显像资料进行分析。结果：１０８ 例中５１ 例有骨转移，阳性率为４７ ．２ ％ ，其中单发转移灶１１ 例，多发转移灶４０ 例。肺癌骨转移以腺癌阳性率最高（ Ｐ＜ ０．０１）；不同区域骨转移分布的发生率有差别（Ｐ＜０．０１），以胸肋部最为多见；而不同类型肺癌在同一区域骨转移发生率无差异（ Ｐ＞０ ．０５） 。结论：核素骨显像诊断肺癌骨转移准确率高，发现早，为一种安全有效的方法。

Purpose:To evaluate the value of radionuclide bone imaging in diagnoisis of bony metastasis of lung cancer Methods:280 cases of bone scanning in lung cancer patients from 1994 to 1998 were analyzed and 108 cases were proved to be lung carcinomas by pathology (including 59 squamous cell carcinomas,29 adenocarcinomas and 20 undifferentiated carcinomas).Results:There were 47.2% positive imaging(51/108) of bony metastasis.Among these cases,11 were single metastasis lesion as well as 40 were multiple metastasis.The positive finding in adenocarcinoma was the highest in the cases of lung carcinomas with bony metastasis ( P <0.01)。The metastasis in different region had a different occurrence rate ( P <0.01),and the chest was the most frequent metastasis region.The distribution of same region in the different types lung carcinomas had no significant difference( P >0.05).Conclusion:The bone radionuclide imaging for lung carcinomas with bony metastasis is a safe,valid and accurate method by which the early-stage lesions can also be found.