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帕利哌酮缓释片与利培酮片治疗精神分裂症的临床分析 被引量:4

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摘要 目的:比较分析帕利哌酮缓释片与利培酮在精神分裂症临床治疗上的差异,并研究帕利哌酮缓释片对患者社会功能的影响。方法:分析比较30例利培酮治疗患者与26例帕利哌酮缓释片治疗患者的临床疗效。结果:SDSS量表评定两组治疗前后相比均有明显差异,帕利酮缓释片疗效明显优于利培酮(p<0.01)。TESS量表评定两组相较差异明显,但两组副反应不同,帕利哌酮组副反应明显少于利培酮组(p<0.01)。BPRS量表评定两组治疗前后差异明显,但两组间治疗后无明显差异。结论:利培酮与帕利哌酮缓释片对精神分裂症的阴性和阳性症状均有疗效,但相较而言,经帕利哌酮缓释片治疗的患者,其社会功能优于利培酮治疗组。帕利哌酮缓释片治疗的患者能够快速恢复学习与职业工作等能力,责任心、自信心和计划性均改善明显,对社会活动的兴趣提升,其疗效十分显著,值得推广。
作者 刘红英
出处 《求医问药(下半月刊)》 2011年第10期468-469,共2页 Seek Medical and Ask The Medicine
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