踝臂指数与冠心病的相关性研究

目的研究踝臂指数（ABI）与冠心病的相关性。方法选择132例经冠状动脉造影的患者，采用日本Colin公司生产的VP1000全自动动脉硬化测定仪测定ABI，分析ABI与冠状动脉病变Gensini评分、病变支数的相关性。结果冠心病组与非冠心病组比较，ABI差异有统计学意义（P〈0．05），且ABI值无病变组高于单支病变组（P〈0．05），单支病变组高于双支病变组（P〈0．05）、双支病变组又高于3支病变组。用stepwise多元回归分析显示，入选患者的ABI是影响Gensini评分独立因素，表明ABI是冠状动脉病变及其严重程度的预测因子。结论踝臂指数与冠心病关系密切，有助于评价、预测冠状动脉病变严重程度。

Objective To test the ankle -brachial index （ABI） and coronary heart disease were positively correlated. Methods 132 patient s who had taken the coronary angiography or percutaneous coronary intervention were recruited. All the patients were checked for ABI by automatic analysis system of angioselerosis. The correlation of ABI and coronary lesion （,ensini score was evaluated, and the prediction evaluation on the extent of coronary lesion was analyzed. Results The difference of ABI between coronary group and control group was significant respectively （ P 〈 0. 05 ）. The ABI in control group was higher than in single branch occlusin group（ P 〈0.05 ） ;the ABI in single branch oeclusin group was higher than double branch occlusion group（ P 〈0. 05）;the AB1 in double branch occlusion group was higher than three branch occlusion. Multi variablestepwise regression analysis showed that ABI is independent factor of Gensini score. Conclusion ABI and coronary heart disease are positively correlated.