摘要
目的 首次探讨了帕金森病(PD)的X-刀治疗,为PD找出了一条新的治疗途径。方法 8 例难治性PD病人,采用X-刀1 次140 Gy 损毁VIM 治疗2 例;140 Gy 分2 次治疗4 例;165 Gy 3 次治疗2 例;每次间隔24 h。结果 X-刀治疗后3~24 个月随访,8 例病人消除或改善了震颤症状;轻度缓了僵直和运动减少症状;无并发症发生。神经心理学检查无显著改善。结论 X-刀可安全、无创治疗难治性PD;震颤症状改善显著;神经心理学指标短期无恢复。
To evaluate the effects of X knife treatment of Parkiusonism and their outcome.Methods 8 parkinson disease(PD) patients were treated by X knife. 2 patients were managed by single full dose of 140 Gy, 4 patients were treated by fractionated irradiation 140 Gy for 2 times, 2 patients were treated by fractionated irradiation by 165 Gy for 3 times.Results 3~18 months later, the tremor of 8 patients disappeared or relieved significantly, the rigidity and bradykinesia were relieved slightly. No complication has been observed. Restoring of neuropsychological improvements were not observed.Conclusions PD treated by X knife is safe, patients tremor can be relieved significantly, but neuropsychological index was not changed in this short period of time.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
1999年第6期324-325,共2页
Chinese Journal of Gerontology
基金
北京市科委资助课题
关键词
SRNS
X-刀
帕金森病
治疗
Stereoradiographic Neurosurgery(SRNS) X knife(gamma knife) Parkinsonism (Original paper see page 324)