713例糖尿病湿性坏疽细菌感染特点

The characteristics of the bacterial infection of 713 cases of diabetic moist gangrene

目的了解糖尿病湿性坏疽的细菌感染特点,使临床选择抗菌药物治疗更有针对性。方法取糖尿病湿性坏疽分泌物进行需氧菌、真菌培养及厌氧菌培养。结果 713例患者中,细菌培养结果阳性率为100%,共培养出1256株细菌,其中革兰阳性菌570例(45.4%)、革兰阴性菌326例(26.0%)、厌氧菌298例(23.7%)、真菌62例(4.9%)。结论糖尿病湿性坏疽感染菌谱特点是革兰阳性菌>革兰阴性菌、厌氧菌>真菌。革兰阳性菌以金黄色葡萄球菌为主,革兰阴性菌以大肠埃希氏菌为主,厌氧菌以二氧化碳嗜纤维杆菌和产气荚膜梭菌为主,真菌以白色念珠菌为主。

【Objective】 To comprehend the characteristic of diabetes moist gangrene infection,making clinical choice of antibiotics more targeted.【Methods】 Taking diabetes moist gangrene secretions to cultivate bacterial.【Results】 In 713 cases of patients,we cultivated 1256 strains of bacteria（gram-positive bacilli 45.4%,gram-negtive bacilli 26.0%,anaerobic 23.7%,fungi 4.9%,）,the positive rate of bacterial culture is 100%.【Conclusion】 The characteristic of infected bacteria spectrum of the diabetes moist gangrene is gram-positive bacteria more than gram-negative bacteria,anaerobic bacteria more than fungi,while staphylococcus aureus,escherichia coli,capnocytophaga and perfringens,and candida albicans is the main pathogenic bacteria in these four types of bacteria.