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固体脂质纳米粒的质量及稳定性影响因素 被引量:1

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摘要 固体脂质纳米粒作为新型纳米药物载体,具有靶向、缓控释作用,且毒性低,较稳定,适于多种用途给药。但由于其体系的复杂性、多态性,其质量控制及稳定性方面还存在许多问题,如载药量低、突释现象和包封率低、药物析出和聚集、过冷态及凝胶化等问题。这也是获得性能良好、稳定的固体脂质纳米给药系统需要解决的症结所在。
出处 《医药导报》 CAS 2011年第12期1617-1620,共4页 Herald of Medicine
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