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子痫前期表观遗传学研究进展 被引量:2

子痫前期表观遗传学研究进展
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摘要 子痫前期(pre—eclampsia,PE)是妊娠20周以后出现的以高血压[收缩压≥140mmHg和(或)舒张压≥90mmHg](1mmHg=0.133kPa)和蛋白尿(尿蛋白≥300mg/24h)为主要表现的多系统综合征,是妊娠最常见的并发症之一,发生率约为2%-8%,是孕产妇死亡的重要原因,严重威胁母婴健康。虽然很多研究者长期致力于其病因及发病机制的研究,但至今尚没有一种学说可以完全解释该病的发病机制。
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2011年第12期947-949,共3页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 子痫前期 发病机制 表观遗传学 pre-eclampsia pathogenesis epigenetics
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参考文献20

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