胆囊炎患者血脂变化及其与中性粒细胞的相关性

Changes of blood lipids level and its correlation with neutrophils level in patients with cholecystitis

目的探讨胆囊炎患者血脂水平的变化及其与中性粒细胞(NEU)的相关性,以鉴别急性胆囊炎和慢性胆囊炎。方法分别用全自动血细胞分析仪和全自动生化分析仪检测急性胆囊炎、慢性胆囊炎和健康对照组的NEU、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)。结果与健康对照组相比,急性胆囊炎患者TG水平显著下降,差异有统计学意义(P<0.05),NEU水平显著升高,差异有统计学意义(P<0.05);慢性胆囊炎患者TG水平显著下降,差异有统计学意义(P<0.05)。健康对照组中,TCH、LDL-C均与NEU呈显著负相关,r值分别为-0.528和-0.510,P<0.05。结论急性胆囊炎和慢性胆囊炎患者TG下降,急性胆囊炎患者NEU升高;健康对照组的TCH和LDL-C均与NEU呈显著负相关。

Objective To discuss the changes of blood lipids level and its correlation with neutrophils level in cholecystitis for identifying acute cholecystitis and chonic cholecystitis.Methods Neutrophils（NEU）,total cholesterol（TCH）,triglyeride（TG）,high density lipoprotein cholesterol（HDL-C）,low density lipoprotein cholesterol（LDL-C） in acute cholecystitis,chonic cholecystitis and normal control group were detected respectively with the automatic cytoanalyzer and automatic biochemistry analyzer respectively.Results Compared with normal control group,the TG level of acute cholecystitis and chonic cholecystitis all decreased significantly（P0.05）,while the NEU of acute cholecystitis increased significantly（P0.05）.In the normal control group,the levels of TCH and LDL-C were negatively correlated to NEU.The coefficient correlation was-0.528（P0.05） and-0.510 respectively（P0.05）.Conclusion TG level of acute cholecystitis and chonic cholecystitisall decreases,while NEU of acute cholecystitis increases.The levels of TCH and LDL-C are negatively correlated to NEU in the normal control group.