老年人共病与认知功能关系的初步研究

The association of comorbidity with cognitive function in the elderly

目的探讨老年人共病与认知功能关系。方法选择2010年在空军总医院行年度体检的军队离退休老干部160名,调查其慢性病患病情况,并采用简易精神状态量表(MMSE)进行认知功能评估。结果患2～4种疾病者占50.6%(81例),患5种及以上疾病者占36.3%(58例)。老年人认知功能下降者占25.6%(41例)。多元线性回归分析显示,MMSE评分与年龄、疾病数量、脑卒中、高血压、房颤、心衰呈负相关。患病种类多的老年人,患5种及以上其认知功能水平显著下降(t=2.624,P<0.05)。结论老年人共病发生率高,共病以及疾病种类多是老年人认知功能下降的危险因素。

Objective To evaluate the relationship between comorbidity and cognitive function in the elderly.Methods The data from 160 military retired cadres aged 65 years old and move were analyzed in the 2010 heath interview survey.The prevalence of chronic diseases was obtained.Cognitive function was assessed by the mini-mental state examination（MMSE）.Results 50.6% of the elderly had two to four types of diseases,and 36.3% had five or more diseases.The prevalence of cognitive impairment was 25.6%.Multiple linear regression analysis showed that MMSE score was negatively correlated with age,the number of disease,stroke,hypertension,heart failure and atrial fibrillation.Those with more medical diseases（five or more）had lower cognitive functions.Conclusion In elderly population,the prevalence of comorbidty was high.Comorbidity and the accompanied diseases were the risk factors of cognitive function impairment in the elderly.