单侧湿性型老年性黄斑变性对侧眼的吲哚青绿血管造影观察

Indocyanine green angiographic findings in contralateral eyes of patients with unilateral exudative age related macular degeneration

目的 探讨单侧湿性型老年性黄斑变性（ａｇｅ－ｒｅｌａｔｅｄ ｍ ａｃｕｌａｒｄｅｇｅｎｅｒａｔｉｏｎ，ＡＭＤ）对侧眼的吲哚青绿血管造影（ｉｎｄｏｃｙａｎｉｎｅ ｇｒｅｅｎ ａｎｇｉｏｇｒａｐｈｙ，ＩＣＧＡ）特征及其临床意义。 方法 对７０例一眼为湿性型ＡＭＤ的患者对侧眼作眼底彩色照相、荧光素眼底血管造影（ｆｕｎｄｕｓ ｆｌｕｏｒｅｓｃｅｉｎ ａｎｇｉｏｇｒａｐｈｙ，ＦＦＡ）以及ＩＣＧＡ检查，并对其眼底荧光图像进行比较和分析。 结果 对侧眼的ＩＣＧＡ特征有：①玻璃膜疣可呈现弱荧光、强荧光及正常荧光等表现；②１４ 只眼ＩＣＧＡ中晚期出现强荧光斑；③１３ 只眼呈现有一个或多个片状脉络膜充盈缺损；④１８ 只眼ＩＣＧＡ中晚期出现簇状强荧光小点。 结论 ＩＣＧＡ 能较好评价单侧湿性型ＡＭＤ对侧眼病变损害程度。

Objective To analyse the indocyanine green angiographic findings in contralateral eyes of patients with unilateral exudative age related macular degeneration(AMD). Methods Fundus photograph,fundus fluorescein angiography(FFA) and indocyanine green angiography(ICGA) were performed in a series of 70 patients with unilateral AMD and drusens and pigmentary changes in the macular region in contralateral eyes.The findings of fluoroangiograms were observed and analysed. Results ICGA revealed the characteristics of the contralateral eyes as follows:(1)Drusen could be hypofluorescent,hyperfluorescent or normal fluorescent;(2)14 eyes revealed plaque like late hyperfluorescent;(3)13 eyes revealed choroidal filling defect;(4)18 eyes revealed pindot like clusters of late hyperfluorescence. Conclusion ICGA is useful in evaluating the lesions and circulation disturbance of the contralateral eye,and may help to find the risk factors of developing future exudative changes.