老年性黄斑变性锥细胞运动觉功能的变化

Motion perception of cones in patients with age related macular degeneration

目的 观察干性型老年性黄斑变性（ａｇｅ－ｒｅｌａｔｅｄ ｍ ａｃｕｌａｒｄｅｇｅｎｅｒａｔｉｏｎ，ＡＭＤ）患者三种视锥细胞视觉运动觉的变化。 方法 通过随机点运动觉检查方法，分别应用蓝、绿、红视标显示在黄、紫及青色背景，保持视标与背景间等亮度以排除亮度因素的影响，从而分离检查２０只眼ＡＭＤ三种视锥细胞视觉运动觉功能的变化。 结果 ＡＭＤ三种视锥细胞的感觉位移和方向位移阈值，与正常人相比明显受损，发生了弥漫性的损害。 结论 视锥细胞的视觉运动觉，是能够反映干性型ＡＭＤ视功能损害的一个新的测试指标。

Objective To assess the change of the motion perception of cones in patients with AMD. Methods Motion perceptions of B、G and R cones of 20 eyes with dry type AMD were isolated by blue,green and red random dots stimulus displayed on the yellow,purple and blue green background respectively,and keeping equiluminance between stimulus and background. Results The detecting displacement threshold and identifying threshold of motion perception from B,G and R cones were all damaged in eyes with dry type AMD compared with the normal group. Conclusion The abnormal changes of motion perception may reveal preclinical damage of visual function damage in dry type AMD.