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儿童伴血小板生长因子受体β基因重排的髓系肿瘤急变为急性淋巴细胞白血病一例报告附文献复习

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摘要 伴血小板生长因子受体β（PDGFRβ）基因重排的髓系肿瘤是一种较罕见的血液系统肿瘤，以髓系增生异常、嗜酸粒细胞增多、PDGFRβ基因重排为主要特征。此肿瘤最常见的染色体易位为t（5；12）（q33；p13），导致位于5号染色体的PDGFRβ基因与12号染色体短臂的TEL基因并置，
作者 柏露 程翼飞 王彬 江倩 张乐萍
机构地区 北京大学人民医院儿科 北京大学人民医院血液病研究所
出处 《中华血液学杂志》 CAS CSCD 北大核心 2011年第12期871-873,共3页 Chinese Journal of Hematology
关键词 血小板生长因子受体 急性淋巴细胞白血病 髓系肿瘤 基因重排 文献复习 PDGFRβ 嗜酸粒细胞增多 急变
分类号 R733.71 [医药卫生—肿瘤]
  • 相关文献

参考文献14

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二级参考文献23

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中华血液学杂志
2011年 第12期

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