屎肠球菌SF-GA12对仔猪腹泻及生长性能的影响

Effects of Enterococcus Faecium SF - GA12 on Diarrhoea and Performance of Piglets

本试验采用双盲试验的方法考察屎肠球菌SF—GA12对仔猪从出生到断乳期间腹泻及生长性能的影响。将114只母猪随机分成试验组54只、对照组60只。对试验组和对照组所产下的仔猪进行试验。（1）仔猪出生后前三天口服给予凝胶制剂1g／只，试验组合菌2．8×10^9CFU／g。（2）出生后第四天到断乳，所有仔猪口服给予100mL糖液制剂（6g／L），试验组另外补充菌液1．26×10^9CFU／只，2次／天。（3）发生腹泻的仔猪分别补充葡萄糖液100～200mL／日1周到2周；试验组葡萄糖液合菌2．9×10^8CFU（第一周）、5．8×10^8CFU（第二周及以后）。以腹泻引起的机体损伤程度进行评分：1分，没有腹泻；2分，只发生腹泻：3分，腹泻、嗜睡、可视粘膜发白，体侧皮肤松弛。结果：试验组与对照组的窝产仔数和断奶期日龄没有差异（P〉0．05）；腹泻发生率，试验组14．8％，对照组40．0％（P〈0．05）；腹泻持续时间两组均为2．2±0．81天（P〉0．05）；腹泻评分，试验组1．2±0．54，对照组1．5±0．54（P〈0．05）；日增重，试验组比对照组高17g/天（P〈0．05）。结论：从仔猪出生到断乳，每日给予1：7服屎肠球菌E．faecium SF—GA12可以降低腹泻的发生率，提高生产性能，提高日增重。然而，对于已发生腹泻的仔猪，添加该菌并没有多大作用。

This placebo - controlled double - blind study was conducted to evaluate effects of Enterococcus faecium SF- GA12（EcF） orally given from birth to weaning on diarrhoea and performance of piglets. At the first 3 days postnatum （p. n. ） ,piglets from 54 [verum group （VG） ] and 60 [ placebo group （PG） ] sows got 1 g of a gel directly per mouth by a dosing device. Gel for the VG eontained 2.8 × 10^9 colony forming units （CFU） EcF/g. From day 4 p.n. until weaning （24 ±3.2 days p. n. ） a liquid additive was given that administered twice a day 1.26 × 10^9 CFU EcF to each VG piglet. In case of diarrhoea, an electrolyte solution was used which provided daily 2.9 and 5.8 （week 1 and ≥ 2,respectively） × 10^8 CFU EcF per VG piglet. Diarrhoea scores were defined as follows： （i） no diarrhoea;（ii） piglets developed diarrhoea,but were vital and （iii） piglets suffered from diarrhoea and additionally looked pale, developed rough coat,showed slackening of the flank and lethargy. Counts of viable born, stillborn and weaned piglets were normal and not different between groups （ P 〉 0.05 ）. Placebo group vs. VG piglets suffered more frequently from diarrhoea （40.0 vs. 14.8% ,P 〈0.05）. Duration of diarrhoea was not affected by feeding EcF （2.2 ±0.81 days, P 〉 0.05 ）. Diarrhoea score was lower in VG vs. PG （1.2 vs. 1.5 ±0.54, P 〈 0.05 ） and the daily weight gain （DWG） was higher by 17 g/day （P 〈 0.05 ）. Results suggested that the daily oral supplementation of EcF from birth to weaning reduces the portion of piglets suffering from diarrhoea. This may improve performance, as the higher DWG indicates. In contrast, no obvious benefit seemed to result from an additional supply of EcF via electrolyte solution when diarrhoea was always present.