期刊文献+

比阿培南侧链的合成方法综述

下载PDF
导出
摘要 本文通过对比阿培南侧链的结构分析,对合成此化合物的三个关键步骤:吡唑烷环A、1,2,4-三氮唑环B和巯基的引入方法进行了综述。
出处 《天津化工》 CAS 2011年第6期4-5,共2页 Tianjin Chemical Industry
  • 相关文献

参考文献6

  • 1Kumagai, T.; Tamai, S.; Abe, T.; Nagase, Y.; Inoue, Y. and Nagao, Y. A Facile Synthesis of Mercaptopyrazolidine Useful for the construction of the Pendant Moiety of 1β-Methylcabapenem L-627 [J]. Heterocycles, 1994, 37(3):1521-1527.
  • 2Wildonger, K.J. and Ratcliffe, W.R. Heteroaryliumthio Substituted Carbarpenem Derivatives: Synthesis and in vitro Activity of 1β- Methyl-2-(Dihydropyrolotrizaoliumthio) carbapenems [J]. J, Anatibiotics, 1993, 46(12):1866-1882.
  • 3Kumagai, T.; Tamai, S.; Abe, T.; Matsunaga, H.; Hayashi, K.; Kishi, I.;Shiro, M. and Nagao, Y. New Straightforward Synthesis and Characterization of a Unique 1β-Methylcarbapenem Antibiotic Biapenem Bearing a σ--Symmetric Bicyelotriazoliumthio Group as the Pendant Moiety [J]. J. Org. Chem. 1998, 63(23):8145-8149.
  • 4石和鹏,郑忠辉,金洁,刘浚.比阿培南关键中间体6,7-二氢-6-巯基-5H-吡唑[1,2-α][1,2,4]三唑内鎓氯化物的合成[J].中国新药杂志,2005,14(3):319-322. 被引量:2
  • 5石和鹏,郑忠辉,金洁,刘浚.比阿培南关键中间体的合成工艺改进[J].中国药物化学杂志,2005,15(1):45-47. 被引量:5
  • 6刘相奎,杨玉雷,朱雪焱,袁哲东.比阿培南的合成[J].中国医药工业杂志,2006,37(12):793-796. 被引量:5

二级参考文献14

  • 1Hara K, Baba S, Matsumoto F, et al. Clirfical evaluation of biapenem in various infectious diseases[J]. Jpn J Antibiot, 1999, 52 (11) : 629 - 660.
  • 2Perry CM, Ibbotson T. Biapenem[J]. Drugs, 2002, 62(15) :2221 - 2234.
  • 3Toshio K,Satoshi T, Tqkao A, et al. New straightforward synthesis and characterization of a unique 1β-methylcarbapenem antibiotic biapenem rearing a σ-symmetric bicyclotriazoliumthio group as the pendant moiety[J] .J Org Chem, 1998, 63(23) :8145 - 8149.
  • 4Wildonger KJ, Ratcliffe RW. Heteroarylliumthio substituted carbapenem derivatives:synthesis and in vitro activity of 1β-methyl-2-(dihydripymolotriazoliumthio) carbapenems[J] .J Antibiot, 1993, 46(12) : 1866- 1882.
  • 5Perry CM,Ibbotson T.Biapenem[J].Drugs,2002,62 (15):2221-2234.
  • 6Wildonger KJ,Ratcliffe RW.Heteroarylliumthio substituted carbapenem derivatives:synthesis and in vitro activity of 1β-Methyl-2-(dihydropyrrolotriazoliumthio) carbapenems[J].J Antibiot,1993,46(12):1866-1882.
  • 7Toshio K,Satoshi T,Tqkao A,et al.New straightforward synthesis and characterization of a unique 1β-methylcarbapenem antibiotic biapenem rearing a σ-symmetric bicyclotriazoliumthio group as thependant moiety[J].J Org Chem,1998,63(23):8145-8149.
  • 8Kumagai T,Abe T,Fujimoto Y,et al.Mild and chemoselectivecleavage of p-nitrobenzyl esters and p-nitrobenzyloxycarbonyl amines with zinc dust[J].Heterocycles,1993,36(8):1729-1734.
  • 9Hara K,Baba S,Matsumoto F,et al.Clinical evaluation of biapenem in various diseases[J].Jpn J Antibiot,1999,52 (11):629-660.
  • 10Perry CM,Ibbotson T.Biapenem[J].Drugs,2002,62 (15):2221-2234.

共引文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部