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MMP-9和MMP-13在非小细胞肺癌组织中的表达及意义 被引量:5

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摘要 目的研究MMP-9、MMP-13在非小细胞肺癌(NSCLC)组织中的表达,及其与NSCLC生物学行为的关系。方法应用免疫组织化学(S-P)法染色技术测定60例NSCLC组织标本的MMP-9、MMP-13的表达情况。结果 MMP-9、MMP-13在NSCLC组织中的阳性表达率显著高于良性肺病变组织;MMP-9、MMP-13在腺癌中表达显著高于在鳞癌中;随肿瘤病理分级的增高、淋巴结转移出现,MMP-13表达有增高趋势。结论 MMP-9、MMP-13与NSCLC临床生物学行为有关。
出处 《广东医学》 CAS CSCD 北大核心 2011年第24期3238-3240,共3页 Guangdong Medical Journal
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同被引文献43

  • 1周建华,王文祥,文继舫,曹慧秋,沈明.MMP_2、MMP_9、TIMP_1、TIMP_2在非小细胞肺癌中的表达及临床病理学意义[J].实用预防医学,2006,13(1):23-26. 被引量:11
  • 2顾莹莹,刘芳,陈国勤,刘慕嫦,胡帅尔,莫明聪,林云恩.非小细胞肺癌MMP-s和TIMP-s的表达与转移及预后分析[J].中国热带医学,2006,6(11):1949-1952. 被引量:7
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