摘要
目的探讨腹膜原发性腺癌的病理形态学特征、诊断及鉴别诊断。方法对3例腹膜原发性腺癌进行形态学观察及免疫组化标记,并结合文献复习。结果患者均为老年女性,平均年龄67.7岁,以腹胀、腹水为主要临床表现;组织学表现2例为浆液性乳头状腺癌,1例为黏液腺癌。免疫组化:EMA、广谱CK、CEA、p53均阳性。结论腹膜原发性腺癌罕见,预后差,与卵巢癌、恶性间皮瘤及胃肠道转移癌易混淆;应依据形态学特点、结合免疫组化结果鉴别。
Objective To investigate the pathological features,diagnosis and differential diagnosis of primary peritoneal adenocarcinoma.Methods 3 cases of primary peritoneal adenocarcinoma were studied by light microscopy and immunohistochemistry,and the literature were reviewed.Results All cases were older female with a mean age of 67.7 years and the common clinical symptoms were abdominal distention and ascites,two cases were identified as serious papillary adenocarcinoma and the other was diagnosed as mucinous adenocarcinoma.Immunohistochemical staining showed positive in EMA,pan-CK,CEA,p53.Conclusion Primary peritoneal adenocarcinoma is a rare neoplasm with poor prognosis,which is easily confused with ovary carcinomas,malignant mesothelial tumors and metastatic tumors of digestive system,and immunohistochemistry helps in the differential diagnosis,combined with morphologicl features.
出处
《医学综述》
2011年第23期3666-3668,共3页
Medical Recapitulate
关键词
腹膜原发性腺癌
临床病理
免疫组化
鉴别诊断
Primary peritoneal adenocarcinoma
Clinical pathology
Immunohistochemistry
Differential diagnosis
