“病-证-方-药”结合探析左金丸配伍的科学内涵

Exploration on scientific connotation of compatibility of Zuojin Wan based on "disease-syndromes-formulas-medicines" binding mode

"病-证-方-药"结合研究有利于揭示经典方剂的配伍规律及作用机制的科学内涵。在该文中,以左金丸为模式经典方,从中医对肝火犯胃证的病因病机认识、现代病理药理的阐释、左金丸的方解及性味归经、药效物质及其药理作用多角度出发,以期揭示左金丸的配伍规律和性味归经的科学内涵,为现代中药复方开发提供思路。

Disease-syndromes-formulas-medicines binding mode is benefit to reveal the scientific connotation of the compatibility and mechanism of classical prescriptions of traditional Chinese medicine（TCM）. In this article, Zuojin Wan was used as a model prescription, with the etiology and pathogenesis of liver-fire invading stomach in TCM, and modern pathological and pharmacological interpretation, the compatibility, nature-flavour, channel tropism, the active substance and pharmacology of Zuojin Wan were explained, in order to reveal the compatibility, nature-flavour and channel tropism of Zuojin Wan, and to provide ideas for the development of modern compound prescription.