C-反应蛋白与结肠腺瘤的相关性

The relationship between C-reactive protein and colon adenoma

目的:探讨C-反应蛋白(CRP)与结肠腺瘤之间的相关性。方法:通过病例对照研究方法及多元回归分析,比较对照组及病例组两组间的C-反应蛋白浓度是否有显著差异。结果:病例组不同年龄女性的CRP值比较,差异无统计学意义(P>0.05),病例组不同年龄男性的CRP值比较差异具有统计学意义(P<0.05),对照组不同年龄男性及女性的CRP值比较差异无统计学意义(P>0.05),不同年龄段病例组及对照组男、女性的CRP值经较差异均具有统计学意义(P<0.05)。逐步线性多元回归分析发现年龄、身高、体重均可影响两组男性、女性的CRP值。结论:CRP与结肠腺瘤有相关性,但是受年龄、身高、体重的影响,缺乏特异性,因此,不能作为筛查结肠腺瘤及判断预后的特异性指标。

Objective To observe the relationship between C-reactive protein（CRP） and colon adenoma.Method To compare the differences of CRP in the experimental group and the control group by case control and multiple regression analysis.Results There is no difference of CRP among different females in the experimental group（P0.05）;there is significant difference in different males in the experimental group（P0.05）.The differences among the different groups of female and males in the control are not significant（P0.05）.The differences among the different groups of female and males in the experimental and control are significant（P0.05）.Age,height and weight can influence the concentration of CRP.Conclusion CRP is relative to colon adenoma,but there is no specificity.