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抗生素缓释系统治疗慢性骨髓炎的研究进展 被引量:4

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摘要 慢性骨髓炎的传统治疗包括感染坏死组织‘清创,消灭死腔,骨组织修复,足够的软组织覆盖,全身应用抗生素。但长期、全身、大剂量使用抗生素,副作用容易显现。而单纯手术治疗失败率高,复发率高,如同时伴大面积的骨缺损,需要再次行植骨手术,治疗将更为困难。基于全身用药的种种不足,
出处 《医学临床研究》 CAS 2011年第11期2144-2147,共4页 Journal of Clinical Research
基金 广东省卫生厅科研基金(No:A2010036)
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  • 1何斌,王云华,黎逢峰,袁同洲,许诺.OsteoSet-骨移植替代物在修复骨缺损中的应用[J].生物骨科材料与临床研究,2005,2(3):9-10. 被引量:3
  • 2Marti - Carvajal A J, Agreda - Perez L H. Antibiotics for treating osteomyelitis in people with sickle cell disease[ J]. Cochrane Data- base Syst Rev. 2012, 12: D7175.
  • 3Moenster R P, Linneman T W, Call W B, et al. The potential role of newer gam - positive antibiotics in the setting of osteomyelitis of adults[J]. J Clin Pharm Ther. 2013, 38(2) : 89 -96.
  • 4Lazaro - Martinez J L, Aragon - Sanchez J, Garcia - Morales E. Response to comment on Lazaro - Martinez et al. Antibiotics versus conservative surgery for treating diabetic foot ostcomyelitis: a ran- domized comparative trial. Diabetes care 2014 ;37:789 - 795 [ J]. Diabetes Care. 2014, 37(5) : e116 -e117.
  • 5Brin Y S, Nyska A, Dorab A J, et al. Biocompatibility of a poly- meric implant for the treatment of osteomyelitis[ J]. J Biomater Sci Polym Ed. 2009, 20(7 -8) : 1081 -1090.
  • 6Gitelis S, Brebach G T. The treatment of chronic osteomyelitis with a biodegradable antibiotic - impregnated implant[ J]. J Orthop Surg (Hong Kong). 2002, 10(1) : 53 -60.
  • 7Brady P W, Brinkman W B, Simmons J M, et al. Oral antibiotics at discharge for children with acute osteomyelitis: a rapid cycle im- provement project[J]. BMJ Qual Saf. 2014, 23(6) : 499 -507.
  • 8Kaczmarczyk J,Sowinski P,Goch M,et al.Complete twelve month bone remodeling with a bi-phasic injectable bone substitute in benign bone tumors:aprospective pilot study[J].BMC Musculoskelet Disord,2015(16):369.
  • 9Morris BJ,Richards JE,Guillamondegui OD,et al.Obesity increases early complications after high-energy pelvic and acetabular fractures[J].Orthopedics,2015,38(10):e881-887.
  • 10Rand BC,Penn-Barwell JG,Wenke JC.Combined local and systemic antibiotic delivery improves eradication of wound contamination:an animal experimental model of contaminated fracture[J].Bone Joint J,2015,97-B(10):1423-1427.

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