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膀胱癌原位新膀胱术后残余尿道黏膜病理改变观察 被引量:1

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摘要 目的:观察膀胱癌原位新膀胱术后不同时期残余尿道黏膜的病理改变,探讨其临床意义。方法:观察1999~2010年期间膀胱癌原位新膀胱手术患者15例,膀胱镜下观察其残余尿道病理改变,并取黏膜组织做镜下观察。同时将19例BPH患者后尿道黏膜作为对照观察。结果:新膀胱组中,≤1年组(4例)1例肿瘤复发,1例为慢性炎症细胞浸润,2例为急慢性炎症政变;1~5年组(8例)3例为慢性炎症改变,5例为腺性膀胱炎政变;≥5年组3例均为腺性膀胱炎改变,且病变程度高于1~5年组。对照组发现后尿道黏膜慢性炎症改变11例,其中并发腺性炎症改变6例。结论:膀胱癌原位新膀胱术后残余尿道黏膜常伴有慢性炎症改变,并随时间延长出现逐渐加重的腺性膀胱炎,长期看存在恶变的风险,但术后残余尿道的肿瘤复发主要由原发肿瘤细胞残留引起。
出处 《临床泌尿外科杂志》 北大核心 2011年第12期946-948,共3页 Journal of Clinical Urology
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