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肠上皮屏障功能的调节与自身免疫性疾病的关系 被引量：2

Relationship between functional regulation of enteric epithelial barrier and autoimmunity disease
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摘要 近年来研究发现很多自身免疫性疾病与肠上皮屏障的功能密切相关,本文着重对肠上皮屏障的基本结构、调控及与自身免疫性疾病的关系作一综述。 Ever increasing research find many autoimmune diseases have close relation to intestinal epithelium barrier. This review will provide a progress on the barrier structure, regulation and relation to autoimmune disease.
作者 李兰
机构地区 内蒙古林业总医院普外科
出处 《胃肠病学和肝病学杂志》 CAS 2011年第11期1065-1068,共4页 Chinese Journal of Gastroenterology and Hepatology
关键词 肠上皮屏障 调节 自身免疫性疾病 Enteric epithelial barrier Regulation Autoimmunity disease
分类号 R574 [医药卫生—消化系统]
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参考文献28

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同被引文献16

  • 1孔武明,龚均,董蕾,陈明霞.肠易激综合征患者肠道屏障——紧密连接改变的示踪电镜观察[J].南方医科大学学报,2007,27(8):1167-1169. 被引量：11
  • 2Bankova LG, Lezeano C, Pejler G,et al. Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions[J]J Immunol, 2014,192 (6) : 2812-2820.
  • 3Wilcz-Villega EM, McClean SO, Sullivan MA, Mast cell tryptase reduces junctional adhesion moleeule-A (JAM-A) expression in intestinal epithelial cellsz im- plications for the mechanisms of barrier dysfunction in 4 irritable bowel syndrome [J]. Am J Gastroenterol, 2013,108(7) : 1140-1151.
  • 4Rychter JW, Van Nassauw L, Brown JK, et al. Im- pairment of intestinal barrier and secretory function as well as egg excretion during intestinal schistosomiasis occur independently of mouse mast cell protease-l[J], Parasite Immunol, 2010,32 (4) : 221-31.
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  • 6Sames J, Yang PC, Soderholm JD, et al. Role of mast cells in chronic stres induced colonic epithelial barrier dysfunction in the raf[J]. Gut, 2001,48(5) :630-636.
  • 7Chichlowski M, Westwood GS, Abraham SN, et al. Role of mast cells in inflammatory bowel disease and inflammation-associated coloreetal neoplasia in IL-10- deficient mice[J]. PLoS One,2010,5(8) ..12220.
  • 8Groschwitz KR, Ahrens R, Osterfeld H,et al. Mast cells regulate homeostatic intestinal epithelial migra- tion and barrier function by a ehymase/Mcpt4-de- pendent mechanism[J], Proc Natl Acad Sci USA, 2009,106(52) :22381-22386,.
  • 9Roberto Berni Canani,Margherita Di Costanzo,Ludovica Leone,Monica Pedata,Rosaria Meli,Antonio Calignano.Potential beneficial effects of butyrate in intestinal and extraintestinal diseases[J].World Journal of Gastroenterology,2011,17(12):1519-1528. 被引量：64
  • 10饶艳霞,陈洁,吴亦栋,顾伟忠.DSS诱导溃疡性结肠炎大鼠模型肝脏紧密连接蛋白的表达改变[J].临床儿科杂志,2012,30(10):967-972. 被引量：5

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胃肠病学和肝病学杂志
2011年 第11期

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