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高血压对女性性功能的影响 被引量:3

Impact of hypertension on female sexual function
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摘要 女性性功能障碍(FSD)是一种与年龄相关的进展性疾病,可能影响多达半数的成年妇女,长期以来,FSD未得到重视。高血压是一种常见病、多发病。高血压及抗高血压药物与FSD有密切关系,其中高血压引起的动脉粥样硬化和内皮功能障碍、抗高血压药物对女性性功能的影响尤为显著,现就高血压对女性性功能的影响机制及研究进展作一综述。 Female sexual dysfunction (FSD) is an age-related progressive disease and may affect up to half of adult women, but it has failed to receive due attention for a long time. Hypertension is a common and frequently encountered disease, and female sexual dysfunction is closely related to hypertension and antihypertensive drugs. Hypertension-related atherosclerosis, endothelial disorder and antihypertensive drugs are important risk factors for female sexual function. This article reviews the mechanisms of hypertension-induced FSD and advances in their studies.
作者 陆林龙 姜睿
出处 《中华男科学杂志》 CAS CSCD 北大核心 2011年第12期1121-1124,共4页 National Journal of Andrology
基金 国家自然科学基金(81070486/H0415) 四川省杰出青年学术技术带头人培育计划(川科计[2010]4号:2010JQ0040)~~
关键词 高血压 女性 性功能障碍 hypertension female sexual dysfunction
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参考文献28

  • 1Archer SL, Gragasin FS, Webster L, et al. Aetiology and management of male erectile dysfunction and female sexual dysfunction in patients with cardiovascular disease. Drugs Aging, 2005, 22 (10) : 823-844.
  • 2Steinke EE. Sexual dysfunction in women with cardiovascular disease: What do we know? J Cardiovasc Nurs, 2010, 25 (2) : 151-158.
  • 3Doumas M, Tsiodras S, Tsakiris A, et al. Female sexual dysfunction in essential hypertension: A common problem being uncovered. J Hypertens, 2006, 24(12): 2387-2392.
  • 4Viigimaa M, Doumas M, Vlachopoulos C, et al. Hypertension and sexual dysfunction: Time to act. J Hypertension, 2011, 29 (2) : 403-407.
  • 5Wieget M, Meston C, Rosen R. The female sexual function index (FSFI): Cross-validation and development of clinical cutoff scores. J Sex Marital Ther , 2005, 31 ( 1 ) : 1-20.
  • 6Hale TM, Hannah JL, Heaton JP, et al. Common therapeutic strategies in the management of sexual dysfunction and cardiovascular disease. Curr Drug Targets Cardiovasc Haemtol Disord, 2005, 5(2) : 185-195.
  • 7Kaya C, Yilmaz G, Nurkalem Z, et al. Sexual function in women with coronary artery disease: A preliminary study. Int J Impot Res, 2007, 19 (3) : 326-329.
  • 8Segraves RT. Emerging therapies for female sexual dysfunction. Expert Opin Emerg Drugs, 2003, 8(2) : 515-522.
  • 9Lanmann EO, Paik A, Rosen RC. Sexual dysfunction in the United States: Prevalence and predictors. JAMA, 1999, 281(6) : 537-544.
  • 10Okeahialam BN, Ogbonna C. Impact of hypertension on sexual function in women. West Afr J Med, 2010, 29(5) : 344-348.

二级参考文献21

  • 1戴玉田,孙则禹,Chitaley K,Webb RC,Mills TM,Lewis RW.应用Rho激酶抑制剂对大鼠阴茎勃起的作用[J].中华男科学杂志,2004,10(8):589-592. 被引量:5
  • 2ODonnell AB, Araujo AB, Mckinlay JB. The health of normally aging men: The Massachusetts Male Aging Study (1987-2004) [J]. Exp Gerontol, 2004, 39(7) :975-984.
  • 3Kimura K, Ito M, Amano M, et al. Regulation of myosin phosphatase by Rho- and Rho-associatedkinase (Rho kinase ) [ J ]. Science, 1996,273 ( 5272 ) :245-248.
  • 4Rees RW, Ziessen T, Ralph DJ, et al. Human and rabbit cavernosal smooth muscle cells express Rho-kinase [ J ]. Int J Impot Res,2002,14( 1 ) :1-7.
  • 5Chitaley K, Wingard C J, Clinton Webb R, et al. Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway[J]. Nat Med, 2001, 7( 1 ) :119-122.
  • 6Mills TM, Chitaley K, Lewis RW, et al. Nitric oxide inhibits RhoA/Rho-kinase signaling to cause erection[J]. EurJ Pharmacol, 2002, 439(1-3):173-174.
  • 7Sauzeau V, Rolli-Derkinderen M, Marionneau C, et al. RhoA expression is controlled by nitric oxide through cGMP-dependent protein kinase activation [J]. J Biol Chem, 2003,278( 11 ) :9472-9480.
  • 8Mills TM, Chitaley K, Wingard C J, et al. Effect of Rho-kinase inhibition on vasoconstriction in the penile circulation [J]. J Appl Physiol, 2001, 91 (3) : 1269-1273.
  • 9Bibalacqua TJ, Liu T, Musicki B, et al. Endothelial nitric oxide synthase keeps erection regulatory function balance in the penis [J]. Eur Urol,2007, 51 (6) :1732-1740.
  • 10Ming XF, Viswambharan H, Barandier C, et al. Rho GTPase/ Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells[J]. Mol Cell Biol, 2002,22(24) :8467-8477.

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