异丙酚在小儿内眼手术麻醉中的应用

APPLICATION OF PROPOFOL TO THE ANAESTHESIA OF PEDIATRIC INTRAOCULAR SURGERY

目的：比较氯胺酮和异丙酚分别用于小儿内眼手术麻醉的异同点。方法：选择80例小儿择期内眼手术患者.年龄81d～12岁，随机分为氯胺酮＋局麻组和异丙酚＋局麻组。每组40例，观察眼压、循环和术后恢复情况等指标。结果：异丙酚在降低眼压，保持循环系统相对稳定，缩短苏醒时间和减轻术后不良反应等方面均优于氯胺酮。

Aim: To compare the effects of Propofol and Ketamine as an anacesthetic agent for pediatric intraocular surgery. Methods: Eighty cases, ASA I, ranging in age from 81 days to 12 years. Undergoing elective intraocular surgery, were randomly divided into 2 groups. The patients received Propofol 2～3 mg·kg-1 (n = 40, group Propofol) or Ketamine 1～2 mg·kg- 1 (n = 40, group Ketamine) for induction and Propofol 5～8 mg·kg - 1·h - 1 or Ketamine 5 ～10 mg·kg - 1·h -1 for maintenance of aneasthe sia respectively. Results: As compared with those in group Ketamine the intraocular tension decreased significantly in group Propofol. Times to recovery of consciousness were shorter in group Propofol than retching and vomiting during the first 24 postoperative hours in group Propofol was lower than that in group Ketamine. Conclusion: The resuluts suggest that Propofol is a suitable general aneasthetic for pediatric intraocular surgery.