血清降钙素原、C-反应蛋白和血沉联合检测在老年肺炎中的临床价值

Clinical value of serum procalcitonin,C-reactive protein and erythrocyte sedimentation rate in the elder patients with pneumonia

目的探讨血清降钙素原(PCT)、C-反应蛋白(CRP)和血沉(ESR)在老年肺炎诊断、预后及疗效评价中的临床价值。方法对62例老年肺炎患者及52例健康老年人PCT、CRP、ESR检查指标进行比较。结果与对照组相比肺炎患者三项指标均明显升高,有显著性差异(P<0.05)。PCT、CRP、ESR的诊断敏感性分别为90.3%、83.9%、80.6%,敏感性无统计学意义。PCT特异性为98.4%,显著高于CRP、ESR的特异性(79.0%、74.2%),有显著差异性。结论血清PCT、CRP、ESR的测定对老年肺炎有一定诊断价值,特别是PCT水平可以作为早期诊断老年肺炎的重要指标。

Objective To investigate clinical value of the serum procalcitonin （PCT）, C- reactive protein（CRP） and erythrocyte sedimentation rate（ESR） in diagnosis, treatment and condi- tion assessment in the elder patients with pneumonia. Methods Make a comparison of serum PCT,CRP and ESR between 62 elder patients with pneumonia and 52 healthy counterparts. Results The serum PCT^CRP and ESR levels in eider patients with pneumonia group were higher than the control group, it presented significant difference （ P 〈 0.05 ）. The diagnostic sensitivity of PCT, CRP and ESR was 90.3% , 83.9% and 80.6% respectively. The specificity of PCT（ 98.4% ） was higher than CRP and ESR （ 79.0% vs 74. 2% ） , and it presented significant difference. Conclusions The serum PCT, CRP and ESR are very important in diagnosing the elder patients with pneumonia, especially the level of PCT is a important diagnostic index.