碳纳米管场效应晶体管在生物传感器中的应用

Application of Field-effect Transistor Based on Carbon Nanotube in Biosensors

随着禽流感、甲流和其他疾病的出现,发展快速、实时、免标记的生物传感器在早期发现和治疗各种疾病方面有重要的作用。由于单壁碳纳米管(SWNTs)具有独特的一维纳米结构、特殊的电性能、良好的生物相容性和尺寸相容性,这些优点使其在生物传感器领域有巨大的潜力。本文综述了近年来碳纳米管场效应晶体管(CNTFET)作为免标记的生物传感器在检测各种生物大分子,如蛋白质、酶、DNA、癌细胞、病毒、糖类物质等方面的应用。

With the emergence of avian flu, influence A virus and other diseases, the development of rapid, real-time, label-free biological sensors has become increasingly significant at the early detection and clinical diagnoses of various diseases. Single-walled carbon nanotubes （SWNTs） have unique one-dimensional structure, special electrical properties, good biocompatibility and size compatibility, so that the SWNTs have great potential uses in the biosensor fields due to these advantages. This article reviews recent examples of carbon nanotubes field-effect transistor （CNTFET） as a label-free biosensors for detecting a variety of biological macromolecules, such as protein, enzyme, DNA, cancer, virus, carbohydrate and so on.