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原发性肝癌的体外化疗药物敏感性探析 被引量:1

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摘要 目的探究原发性肝癌对体外化疗药物的敏感性。方法选取我院2005年1月至2010年12月间确诊的原发性肝癌患者50例,选用MTT比色法,分别测定原发性肝癌对7种化疗药物的体外敏感性,包括阿霉素(ADM)、5-氟脲嘧啶(5-Fu)、顺铂(DDP)、丝裂霉素(MMC)、长春新碱(VCR)、羟基喜树碱、甲氨蝶呤(MTX)。结果肝癌患者对化疗药物的敏感率由高到低的顺序为羟基喜树碱>5-氟脲嘧啶>丝裂霉素>顺铂>阿霉素>甲氨蝶呤>长春新碱,各组敏感性具有明显的差异(P<0.05)。结论原发性肝癌对化疗药物的敏感性不同,临床治疗应该根据药敏试验的结果进行个体化综合治疗。
作者 崔茹龙
出处 《中国医药指南》 2011年第34期107-108,共2页 Guide of China Medicine
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