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白三烯抑制剂在哮喘治疗中的进展 被引量:2

The progress of treatment with leukotriene inhibitors in patients with asthma
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摘要 目的:介绍白三烯抑制剂治疗哮喘的进展。方法:综述近年来国外有关文献,介绍和评价白三烯抑制剂的临床疗效,不良反应和用法用量。结果:白三烯抑制剂有效地治疗哮喘发作,且副作用较少。结论:白三烯抑制剂临床使用安全有效,是一类新的哮喘治疗药物。 OBJECTIVE:To review the progress of leukotriene inhibitors in the treatment of asthma.METHOD:The recentl literatures on this subject were reviewed.The clinical effect,ADRs,and dosag of leukotriene inhibitors were presented and evaluated.RESULTS:Leukotriene inhibitors proved to be an effective drugs for the treatment of asthma,with less adverse side effect.CONCLUSION:Leukotriene inhibitors is safe and effective in clinical use and may be as an new agent in the treatment of asthma.
出处 《中国现代应用药学》 CAS CSCD 1999年第6期5-7,共3页 Chinese Journal of Modern Applied Pharmacy
关键词 白三烯 白三烯抑制剂 哮喘 药物疗法 leukotrienes,leukotriene inhibitors,asthma
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同被引文献12

  • 1楼红萍.孟鲁司特治疗儿童支气管哮喘80例疗效观察[J].现代实用医学,2006,18(7):488-488. 被引量:7
  • 2Clint DW.Brooks,Andrew O.Stewart,et al.(R)-(+)-N-[3-[5-[(4-Fluoropheny)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea(ABT-761),a second-generation 5-lipoxygenase inhibitor[J].J Med Chem,1995,38(24):4768-4775.
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  • 6Devillier Ph,Bessard G,Advancer CH.Les antagonists des leucotrienes:une approach nouveHe du treatment de l'asthme[J].Rev des Maladies Respiratoirs,1997,14(14):159.
  • 7Crooke ST,Sarau H,Saussy D,et al.Signal transduorion processes for the LTD4 receptor[J].Adv Prostaglandin Thromboxane Leukot Res,1990,20:127.
  • 8Lepeleive ID,Reiss TF,RocheHe F,et al.Montelukast causes prolonged,potent leukotriene D4-receptor antagonism in the airways of patients with asthma[J].Clin Pharmacol Ther,1997,61(1):83.
  • 9Bronsky EA,Kemp JP,Zhang J,et al.Doserelated protection of execfise bronchoconstriction by montelukast,a cysteinyl leukotriene-receptor antagonist,at the and of a once-daily dosing interval[J].Clin Pharmacol Ther,1997,62(5):556.
  • 10廖增顺.白三烯受体阻断药在哮喘防治中的应用[J].新医学,1999,30(5):255-256. 被引量:7

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