儿黄散促进宫颈柱状上皮异位物理治疗后创面修复的临床观察

Clinical Observation of Erhuang Powder′s Promoting the Wound Healing of Cervical Columnar Epithelium Ectopy after Physiotherapy

目的观察儿黄散局部给药对宫颈柱状上皮异位患者经物理治疗后创面修复的疗效。方法 64例中、重度宫颈柱状上皮异位伴有接触性出血患者,按随机数字表法分为治疗组(34例)与对照组(30例)。两组均给予宫颈物理治疗。治疗组自宫颈物理治疗后每隔3天使用儿黄散敷于患处,5次为1个疗程,共治疗2个疗程。观察两组疗效、创面愈合时间、阴道排液量、阴道排液持续时间、创面感染及不良反应情况。结果治疗8周后,治疗组治愈率(85.29%,29/34)明显高于对照组(50.00%,15/30),差异有统计学意义(P<0.01)。治疗组创面愈合时间短于对照组[周,(3.82±0.28)vs(5.13±0.29)],阴道排液量及排液持续时间优于对照组,差异均有统计学意义(P<0.05,P<0.01)。对照组2例出现阴道分泌物增多伴异味感染情况,治疗组未见感染及不良反应。结论儿黄散宫颈局部给药可促进宫颈柱状上皮异位患者物理治疗后的创面修复,提高其治愈率,是一种疗效较为理想且可靠的治疗方法,值得临床推广。

Objective To observe the clinical effects of Erhuang Powder（EHP） in promoting the wound healing of cervical columnar epithelium ectopy after physiotherapy.Methods Sixty-four patients with moderate and severe cervical columnar epithelium ectopy accompanied with contact bleeding were assigned to the treatment group（34 cases） and the control group（30 cases） according to table of random digit.Physiotherapy of the cervix was given to all patients.EHP was externally applied to the affected site of patients in the treatment group once every 3 days.Five times consisted as one therapeutic course,totally for 2 courses.The therapeutic effects,the wound healing time,the vaginal fluid quantity,the vaginal fluid discharge time,the wound infection,and adverse reaction were observed in the two groups.Results The healing rate of the treatment group was 85.29%（29/34）,higher than that of the control group（50%,15/30） after 8 weeks of treatment,showing statistical difference（P0.01）.The average wound healing time of the treatment group（3.82±0.28 weeks） was shorter than that of the control group（5.13±0.29 weeks）,showing statistical difference（P0.05）.The vaginal fluid quantity and the vaginal fluid discharge time in the treatment group were superior to those in the control group,showing statistical difference（P0.05,P0.01）.Increased vaginal secretion accompanied with foreign odor or infection occurred in 2 patients of the control group.No adverse reaction or infection occurred in the treatment group.Conclusions Local application of EHP could promote the wound healing of cervical columnar epithelium ectopy after physiotherapy.It could improve its healing rate.Therefore,it was one ideal and reliable method,and worthy of clinical spreading.