补肾调周法联合曲普瑞林治疗未破裂卵泡黄素化综合征临床观察

Clinical Effects of Shen-nourishing and Menstruation-regulating Method Combined with Triptorelin Acetate Injection on Patients with Luteinized Unruptured Follicle Syndrome

目的研究补肾调周法联合曲普瑞林治疗未破裂卵泡黄素化综合征(luteinized unruptured folliclesyndrome,LUFS)的临床疗效。方法将62例LUFS患者随机分为对照组(30例)和治疗组(32例)。对照组给予曲普瑞林治疗,治疗组给予中药补肾调周法联合曲普瑞林治疗。观察两组排卵率及妊娠率。结果治疗组排卵率高于对照组(85.53%vs 79.07%),差异无统计学意义(P>0.05);妊娠率也高于对照组(56.25%vs30.00%),差异有统计学意义(P<0.05)。结论中药补肾调周法联合曲普瑞林治疗LUFS能够提高患者排卵率及妊娠率,说明根据卵泡发育的不同时期采用不同的中药行补肾调周治法,可改善LUFS患者卵巢功能。

Objective To study the clinical effects of Shen-nourishing and menstruation-regulating method（SNMRM） combined with Triptorelin Acetate Injection（TAI） on patients with luteinized unruptured follicle syndrome（LUFS）.Methods Sixty-two LUFS patients were randomly assigned to the treatment group and the control group.TAI was given to patients in the control group while SNMRM＋TAI was given to those in the treatment group.The ovulation rate and the pregnancy rate were observed in the two groups.Results The ovulation rate in the treatment group was higher than that in the control group,but without significant difference（85.53% vs 79.07%,P0.05）.The pregnancy rate was significantly higher in the treatment group than in the control group（56.25% vs 30.00%,P0.05）.Conclusion Treatment of LUFS by SNMRM＋TAI could improve the ovulation rate and the pregnancy rate,indicating that LUFS patients′ ovary functions could be improved by using different menstruation regulating methods during different follicular development phases.