帕金森病患者医院感染临床分析

Clinical analysis of nosocomial infection in patients with Parkinson disease

目的分析帕金森病患者的医院感染情况,探讨其相关因素,以采取有效的控制措施。方法对2008年1月1日-2010年12月31日神经内科出院的165例帕金森病患者的医院感染情况进行回顾性调查分析。结果医院感染17例25例次,感染率为10.30%,例次感染率为15.15%;多发生在住院2周内;呼吸道感染最多,占55.43%,其次为泌尿道,占24.00%;共分离出33株病原菌,居首位的为肺炎克雷伯菌,占42.42%;年龄、病程、侵入性操作、抗菌药物预防性应用、住院天数、血浆白蛋白与医院感染的发生相关。结论帕金森病患者的医院感染发生率高,应重视医院感染的相关因素,采取预防治疗措施,减少医院感染发生率,促进患者康复。

OBJECTIVE To investigate the nosocomial infection circumstance in parkinson disease and explore the risk factors of nosocomial infection, so that can obtain the methods of controlling the infection. METHODS A retrospective analysis of nosocomial infection circumstance had been accomplished among 165 Parkinson disease cases from our department ward from Jan 1,2008 to Oct 31,2010. RESULTS It showed cases with nosocomial infection were found among 165 cases. The nosocomial infection rate was 10.30% and case-time rate was 15.15% among inpatients of Parkinson disease. Nosocomial infection mostly took place within the first 2 weeks after patients hospitalized. Among inpatients with nosocomial infection, the respiratory tract infection was the highest （55.43%） ,the second one was the urinary tract （24.00%）. Pathogenic bacteria were mostly the conditional ones. Nosocomial infection was closely related to such factors as age, diseases history, invasive operation, antibiotic prophylaxis,hospitalization days, plasma total protein. CONCLUSION Nosoeomial infection is still a high factors frequent complication in parkinson disease and those related factors should be paid attention to. It is most important step for the rehabilitation of Parkinson disease and the effective control of nosocomial infection.