三白草的化学成分

Chemical constituents from Saururus chinensis(Lour.) Baill

从三白草Saururus chinensis(Lour.)Baill中分离得到7个化合物,经波谱学方法和理化性质分别鉴定为meio-carpin(1),三白草内酰胺(2),马兜铃内酰胺AⅡ(3)、4,5-dioxodehydroasimilobine(4),金丝桃苷(5),槲皮素(6),槲皮苷(7)。化合物1,3,4为首次从三白草属中分离得到。其中化合物1为一种罕见的7,8-裂环木脂素,本文应用ROESY谱和CD谱首次确定了其绝对构型。

Seven compounds were isolated and purified from Saururus chinensis（Lour.） Baill,and were identified as meiocarpin（1）,sauristolactam（2）,aristololactam AⅡ（3）,4,5-dioxodehydroasimilobine（4）,hyperin（5）,quercetin（6）,and quercitrin（7） by spectroscopic techniques and physicochemical properties.Compounds 1,3,4 were first isolated from the genus Saururus.Among them,compound 1 is an unusual 7,8-secolignan,the absolute configuration of which was first determined as 7′R,8′S on the basis of ROESY and CD spectral studies.