20种中草药对迟缓爱德华氏菌的体外抑菌试验

In Vitro Antibacterial Activity of 20 Chinese Herbs to Pathogenic Edwardsiella tarda

用琼脂扩散法和二倍稀释法测定了20种中草药对迟缓爱德华氏菌(Edwardsiella tarda)(GD080715-1、GD080715-2)的体外抗菌活性。结果表明,五倍子、乌梅、大青叶、石榴皮的抑菌作用明显,最小抑菌浓度(MIC)<6.25 mg/mL,最小杀菌浓度(MBC)<50 mg/mL;吴茱萸和菖蒲有一定的抑菌作用,MBC为50～100 mg/mL;而苦地丁、栀子的抑菌作用不明显,MBC>200 mg/mL。

The antibacterial activity of 20 Chinese herbs to pathogenic Edwardsiella tarda （GD080715-1, GD080715-2）were determined in vitro by agar diffusion method and two fold dilution method. The results showed that Galla, Fructus, Folium and Pericarpium were found to have significant inhibition to the bacterium with minimal inhibitory concentration （MIC） less than 6.25 mg/mL and minimal bactericidal concentration （MBC） less than 50 mg/mL; Fructus and Acorus calamus showed some extent inhibition to the bacterium with MBC of 50 - 100 mg/mL, but bunge corydalis herb and Fructus had no inhibition to the bacterium with MBC of more than 200 mg/mL.