联合检测血清CA153、CEA在诊断乳腺癌术后复发转移中的诊断价值

ClinicaI Value of Combining Detection of Cal53、CEA in Postoperative Breast Cancer Patients with Recrudescent and Metastasis

目的:探讨血肿瘤标志物CA153、CEA联合检测在乳腺癌患者术后复发及转移中的临床价值。方法:选择本院2003～2009年124例乳腺癌患者,均行根治性手术,术后定期随访,将随访结果分成两组,一组为无复发转移,另一组经CT、局部活检或再次手术证实为复发转移,分别检测两组患者血清中的CA153及CEA水平。结果:复发转移患者与未发生复发转移患者的CEA、CA153水平具有显著差异,患者术后CEA、CA153阳性率与复发转移情况具有显著相关。结论:血清CEA、CA153联合检测对乳腺癌术后复发转移有重要的指导意义,值得推广。

Objective： To investigate the clinical siginificance of combisined detection of serum tumor maker CA153 and CEA in patients with recrudescent and metastatic breast cancer. Methods：In 124 Breast cancer patients form 2003 to 2009 year, were performed radical surgery, Follow - up after operation , and results into two groups, one group of no recrudescent and metastasis, another group of the CT, local biopsy or again the operation confirmed for recrudescent and metastasis, two groups of patients were detecting in the serum of CA153 and CEA level. Results： The levels of CA15 -3 and CEA were significant differences in recrudesccnt and metastatic patients compared with non - recrudes- cent and non- metastatic patients. Conclusions： Combisined detection of serum CA153 and CEA may play a guiding role in patients with recrudeseent and metastatic breast cancer.