子癎前期、子癎患者并发可逆性后部白质脑病综合征的MRI表现及临床分析

Evaluation on MRI feature and clinical characteristics of pre-eclampsia and eclampsia complicated with reversible posterior leukoencephalopathy syndrome

目的探讨子癎前期、子癎并发可逆性后部白质脑病综合征(RPLS)的MRI表现及临床特点。方法回顾性分析17例子癎前期、子癎并发RPLS患者的临床资料。结果 17例RPLS均有高血压、头痛,14例恶心、呕吐;13例视力障碍;16例子癎发作;MRI检查大脑后部为主的白质水肿,特别是枕叶,T2WI、FLAIR呈高信号,DWI呈等信号或稍低信号,ADC图呈高信号。结论子癎前期、子癎易并发可逆性后部白质脑病综合征,视力障碍是RPLS的特征表现,MRI检查可明确诊断RPLS。

Objective To evaluate MRI feature and clinical characteristics of pre-eclampsia and eclampsia complicated with reversible posterior leukoencephalopathy syndrome（RPLS）. Methods Clinical data of 17 cases of pre-eclampsia and eclampsia complicated with reversible posterior leukoencephalopathy syndrome were studied retrospectively. Results All the patients presented with hypertension,headache,14 cases with nausea and vomiting,13 cases with disturbance of vision,16 cases with seizure episodes.MRI finding showed edema predominantly in the bilateral posterior cerebral with matter,especially in occipital parietal lobe,hyperintensity on T2WI and FLAIR images,isointensity on DWI and hyperintensity on ADC. Conclusion The pre-eclampsia and eclampsia tended to complicated with RPLS,presenting disturbance of vision as major clinical manifestations.The MRI has an important value in diagnosis of RPLS.