期刊文献+

联合止吐方案预防顺铂所致恶心呕吐的临床观察 被引量:4

Effects of combined antiemetic scheme containing tropisetron on vomitting caused by chemotherapy
下载PDF
导出
摘要 目的观察以托烷司琼为主的联合止吐方案预防化疗患者恶心呕吐的作用。方法选择62例化疗患者,化疗前30 min静脉滴注托烷司琼+地塞米松、泮托拉唑,同时口服胃复安。观察该方案对化疗性恶心呕吐的防治效果及不良反应发生情况。结果托烷司琼加镇吐合剂组在抑制恶心、呕吐等方面明显优于对照组。结论托烷司琼为主的联合止吐方案是较好的预防化疗恶心呕吐的止吐方案,安全有效、值得推广。 Objective To evaluate the prophylactic effects of combined antiemetic scheme containing tropisetron on vomitting caused by chemotherapy.Methods 62 patients with malignant tumors were enrolled in this trial,the combined antiemetic scheme including intravenous transfusion of tropisetron + dexamethasone + pantoprazole were given to patients 30 min before the chemotherapy in study group Then the incidence of vomiting and side effects of these subjects were recorded during the chemotherapy.Results Combined antiemetic scheme containing tropisetron group was superior to control group in the prevention of nausea and vomiting with significant difference(P0.05). Conclusion Tropisetron plus antiemetic mixture for preventing vomitting caused by chemotherapy was effective and safe.
出处 《安徽医学》 2011年第11期1837-1838,共2页 Anhui Medical Journal
关键词 化疗 恶心 呕吐 顺铂 托烷司琼 Chemotherapy Nausea Vomiting Cisplatin Tropisetron
  • 相关文献

参考文献5

二级参考文献38

共引文献44

同被引文献23

  • 1陈鸿利,吾麦尔江.艾麦提,高峻峰,张松岩.顺铂类抗肿瘤药物研究进展[J].承德医学院学报,2005,22(2):150-153. 被引量:7
  • 2张晓静,张频.肿瘤化疗所致恶心呕吐的发生机制和药物治疗的研究进展[J].癌症进展,2006,4(4):348-354. 被引量:126
  • 3郑颖,刘建华,杜敏,向杨,干霞,李霞.多西他赛治疗非小细胞肺癌患者过敏反应的护理[J].护理学报,2006,13(8):62-62. 被引量:17
  • 4陈宏才,罗红彤,蔡伟红.不同剂量5-HT_3受体拮抗剂格拉司琼防治围术期恶心呕吐的临床研究[J].重庆医学,2007,36(18):1859-1860. 被引量:9
  • 5Tomek R,Vrdoljak E,Vrbanec D. Croatian guideliness for prevention of chemotherapy induced nausea and vomiting[J].Lijecnicki Vjesnik,2009,(3/4):49-53.
  • 6Zech K,Steinijans V W,Huber R. Pharmacokinetics and drug interactions-relevant factors for the choice of a drug[J].International Journal of Clinical Pharmacology and Therapeutics,1996,(S 1):S3-S6.
  • 7Blumen H. The interaction between PPI and orthr drugs[J].Drug Safety,2006,(09):769-771.
  • 8Vrabel M. Is ondansetron more effective than granisetron for chemotherapy-induced nausea and vomiting?A review of comparative trials[J].Clinical Journal of Oncology Nursing,2007,(06):809-813.doi:10.1188/07.CJON.809-813.
  • 9Saito M,Aogi K,Sekine I. Palonosetron plus dexamethasone versus granisetron plus dexamethasone for prevention of nausea and vomiting during chemotherapy:a double-blind,double-dummy,randomised,comparative phase Ⅲ trial[J].Lancet Oncology,2009,(02):115-124.
  • 10Yeo W,Mo F K,Suen J J. A randomized study of aprepitant,ondansetron and dexamethasone for chemotherapy-induced nausea and vomiting in Chinese breast cancer patients receiving moderately emetogenic chemotherapy[J].Breast Cancer Research and Treatment,2009,(03):529-535.doi:10.1007/s10549-008-9957-9.

引证文献4

二级引证文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部