MMPI对首发偏执型精神分裂症的价值探讨

MMPI in first-episode paranoid schizophrenia

目的探讨MMPI(明尼苏达多项人格测查表)在首发偏执型精神分裂症中的特征及诊断价值。方法对首发偏执型精神分裂症患者,在未治疗前行MMPI测试,分析其有效测评结果,并与之按1:1匹配正常组对照分析。结果首发偏执型精神分裂症患者组有2个效度量表及7个临床子量表的T分均与正常对照组差异有统计学意义;临床子量表两点测图Pa(偏执)、Sc(精神分裂)模式的T分,患者组与正常对照组差异有统计学意义;MMPI的测试结果无法解决敏感性与特异性间矛盾,存在假阳性与假阴性结果。结论 MMPI对首发偏执型精神分裂症的敏感性与特异性高于正常人群的随机水平,将其作为精神科临床辅助检查工具有一定的实用价值,但无法替代临床精神检查。

Objective To study the characteristics and diagnosis value of MMPI （Minnesota Multiphasic Personality Inventory） in first-episode paranoid schizophrenia. Methods Before the treatment, MMPI was administrated to the patient with first-episode paranoid schizophrenia. Analyzed the efficiency of the survey results and compared the results with that of controls of the same number. Results ignificant differences were found between the patients with first-episode paranoid schizophrenia and healthy controls in two validity scales and T-scores of seven clinical sub-scale. For the T-scores of the MMPI two^point codes types for Pa （paranoid） and Se （schizophrenia）, there was a significant difference between the study and control group. For first-episode paranoid schizophrenia, the MMPI results cannot resolve the contradictions between sensitivity and specificity, the false positive and negative results should be noticed. Condttsion MMPI results were more specific and sensitive compared with the normal controls. However, it cannot replace clinical psychiatric examination for diagnosis of the first-episode paranoid schizophrenia. MMPI could be chosen as an accessory method for clinical psychiatry.