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慢性丙型肝炎病毒感染的治疗:热点、难点和希望 被引量:1

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摘要 2011年3月欧洲肝病年会发布新版《欧洲临床实践指南:丙型肝炎病毒感染的处理》的时候,聚乙二醇干扰素α(PEG-IFNα)联合利巴韦林(RBV)仍然是慢性丙型肝炎的标准治疗方案.但紧随其后,2011年5月两种直接抗HCV药物(direct acting antivirals,DAAs)在美国和欧洲陆续批准上市,即telaprevir和boceprevir两个蛋白酶抑制剂.2011年8月8日,JHepatol在线发表了法国Beaujon医院Asselah撰写的述评,提出DAAs的迅速发展使在PEG-IFNα联合RBV的基础上加用DAAs(三联治疗)成为新的标准治疗方案.这一最新的进展显示了目前慢性HCV感染治疗的热点和随之带来的难点和希望.
作者 魏来
出处 《中华内科杂志》 CAS CSCD 北大核心 2011年第12期993-994,共2页 Chinese Journal of Internal Medicine
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