氯乙酰氯和苯甲酰氯联产工艺的研究

Process for Joint Preparation of Chloroacetyl Chloride and Benzoyl Chloride

研究了三氯甲苯和氯乙酸在催化剂存在下反应生成氯乙酰氯和苯甲酰氯的工艺条件。７０－０ ｇ氯乙酸和０－６ ｇ ＺｎＯ／ＳｎＣｌ２ 混合加热到１２０ ℃，在２～３ ｈ 内滴加１６０－０ ｇ 三氯甲苯，常压蒸馏反应混合物得到８１－０ ｇ 氯乙酰氯，纯度为９９％ ；然后减压蒸馏得到１００－０ ｇ 苯甲酰氯，纯度为９８％ ，收率＞９０％ 。

The reaction of benzotrichloride and chloroacetic acid to form chloroacetyl chloride and benzoyl chloride in the presence of catalyst was studied. Benzotrichloride (160.0g) was added dropwise to a mixture of chloroacetic acid (71.0g) and the catalyst (ZnO/SnCl 2) at 120℃ for 2～3h. The resulting reaction mixture was distilled at atmospheric pressure to give 81.0g chloroacetyl chloride of 99% purity, and then distilled under reduced pressure to give 100.0g benzoyl chloride of 98% purity. The yield was over 90%.